Oph tables
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On October 14, 2021, the provincial data system, CCM, improved documentation of a client's sex. Cumulative counts and counts for all cases in the last 30 days are provided. The new “Presumptive Omicron - B.1.1.529” category represents all COVID-19 cases presumed to be the Omicron variant. The "Lineage Omicron - B.1.1.529" category represents confirmed COVID-19 cases where the Omicron variant was identified by genomic analysis. For a better idea of current trends in COVID-19 cases, we suggest reviewing two metrics on the Monitoring Indicators page of the COVID-19 dashboard: 7-day average of newly reported cases and the reproduction number graph.Īs of 15 December 2021, there are two categories related to Omicron in the "Variants of Concern/Interest and Mutations" section of the OPH Daily COVID-19 Dashboard.
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The database is continuously being updated as cases are investigated and as more information becomes available. For more information about the daily number of COVID-19 cases reported to OPH by the date reported to OPH, please refer to column F of the following Open Ottawa dataset: COVID-19 Demographics and Source of Infection for Cases, Deaths, and Hospitalizations. * Please note the CCM reporting system is a dynamic database and the data on the OPH dashboard represents a snapshot in time. This dashboard applies to Ottawa residents with confirmed COVID-19. A confirmed case is a person with laboratory confirmed COVID-19. Data are extracted from CCM at 3 pm daily and loaded to the dashboard the following day. The CCM is a dynamic disease reporting system that allows for ongoing updates data represent a snapshot at the time of extraction and may differ from previous or subsequent reports. Ottawa Public Health’s COVID-19 Dashboard provides up-to-date information on COVID-19 in Ottawa, including indicators for local monitoring and informing re-opening decisions. Data in this dashboard are based on information extracted from the provincial Case and Contact Management (CCM) solution.
#Oph tables update#
Certain visuals will update sooner than others due to data caching on the Microsoft Power BI server. Further evaluation of nano-OPH as a catalytic bioscavenger countermeasure against organophosphorus chemical warfare agents and pesticides is warranted.Between 11:30 and 12:30 pm, visuals in the dashboard may present conflicting information. In particular, a complete protection against the lethal doses of paraoxon was observed with nano-OPH administered iv and ip as much as 17 h, im 5.5 h and tb 2 h before the intoxication. Moreover, nano-OPH is bioavailable after intramuscular ( im), intraperitoneal ( ip) and even transbuccal ( tb) administration, and has shown ability to protect animals from exposure to a pesticide, paraoxon and a warfare agent, VX.
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The nano-OPH pharmacokinetic parameters are improved compared to the naked enzyme suggesting longer blood circulation after intravenous ( iv) administrations in rats. It also decreases the immune and inflammatory responses to His 6-OPH in vivo as determined by anti-OPH IgG and cytokines formation in Sprague Dawley rats and Balb/c mice, respectively. Incorporation of His 6-OPH in nano-OPH preserves catalytic activity and increases stability of the enzyme allowing its storage in aqueous solution for over a year. The resulting polyion complex, termed nano-OPH, has a spherical morphology and a diameter from 25 nm to 100 nm. A simple and highly efficient catalytic scavenger of poisonous organophosphorus compounds, based on organophosphorus hydrolase (OPH, EC 3.1.8.1), is produced in aqueous solution by electrostatic coupling of the hexahistidine tagged OPH (His 6-OPH) and poly(ethylene glycol)- b-poly( l-glutamic acid) diblock copolymer.